Bos taurus ultralong CDR H3 antibodies

Biological Efficiency Differences Among Bos taurus x Bos taurus andBos indicus x Bos taurus F1-Cross Cows

Abnormal Bovine (Bos taurus L.) Karyotypes1

The addition of BUDR (5-bromodeoxiuridine), a thymine analogue, to cell cultures causes various chromosomic changes, depending on the length of treatment and when the BUDR is incorporated into the DNA molecule. A short BUDR treatment of cells in the second half of the S-phase causes symmetrical chromosome segmentation (Zacharov et al. 1971), while prolonged contact over two division cycles indu...

A comparative study on urinary purine derivative excretion of yak (Bos grunniens), cattle (Bos taurus), and crossbred (Bos taurus x Bos grunniens) in the Qinghai-Tibetan plateau, China.

Two experiments were conducted to determine the urinary purine derivative (PD) excretion rates and to analyze potential variations in PD excretions between yak, Tibetan indigenous cattle, and their crossbreds under similar ecological environment, and to develop prediction equations based on PD excretion for estimating rumen microbial protein supply. Three Tibetan castrated male yaks, and simila...

The origin of CDR H3 structural diversity.

Antibody complementarity determining region (CDR) H3 loops are critical for adaptive immunological functions. Although the other five CDR loops adopt predictable canonical structures, H3 conformations have proven unclassifiable, other than an unusual C-terminal "kink" present in most antibodies. To determine why the majority of H3 loops are kinked and to learn whether non-antibody proteins have...

CDR-H3 diversity is not required for antigen recognition by synthetic antibodies.

A synthetic phage-displayed antibody repertoire was constructed with equivalent chemical diversity in the third complementarity-determining regions of the heavy (CDR-H3) and light (CDR-L3) chains, which contrasts with natural antibodies in which CDR-H3 is much more diverse than CDR-L3 due to the genetic mechanisms that generate antibody encoding genes. Surprisingly, the synthetic repertoire yie...